Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery
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چکیده
منابع مشابه
Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery.
Buccal patches of salbutamol sulfate were prepared using five different water soluble polymers in various proportions and combinations using PEG-400/PG as plasticizers. A 32 full factorial design was used to design the experiments for each polymer combination. Patches were laminated on one side with a water impermeable backing layer for unidirectional drug release. The thickness of medicated pa...
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the purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (ss) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. the influence of various permeation enhancers, such as dimethyl sul...
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The purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (SS) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. The influence of various permeation enhancers, such as dimethyl sul...
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The unidirectional release buccal patches of carbamazepine (CBZ) were designed in total of 36 formulations using a 32 full factorial design. Different hydrophilic polymers were used in the formulation along with chitosan-HPMC matrix. The thickness of the prepared patches varied between 0.3 ± 0.10 and 0.5 ± 0.15 mm. The mass of the patches varied from 142.4 ± 0.22 and 160.2 ± 0.13 mg. The pH of ...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2011
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-011-0011-9